Jeff Good

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CONTACT INFORMATION.

    Jeffrey M. Good
    Dept. Evolutionary Genetics
    Max Planck Institute for Evolutionary Anthropology
    Deutscher Platz 6
    04103 Leipzig
    phone: +49-341-3550-543
    E-mail: jeffrey_good@eva.mpg.de

RESEARCH INTERESTS

    I am broadly interested in the process of speciation and adaptation. My current research focuses on the genetic basis of reproductive isolation among closely related species of house mice (Mus). I am using a variety of approaches to identify genes involved in hybrid male sterility, including genetic crosses among wild-derived inbred lines and hybrid zone mapping in natural populations. Other areas of interest include speciation in chipmunks, sexual selection and the evolution of male reproduction, evolutionary genomics, adaptive evolution in humans, and comparative phylogeography.

PUBLICATIONS

Good, J. M., Dean, M. D., and Nachman, M. W. 2008. A complex genetic basis to X-linked hybrid male sterility between two species of house mice. Genetics 179: 2213-2228.

Green, R. E., Malaspinas, A.-S., Krause, J., Briggs, A. W., Johnson, P. L. F., Uhler, C., Meyer, M., Good, J. M., Maricic, T., Stenzel, U., Prüfer, K., Siebauer, M., Burbano, H. A., Ronan, M., Rothberg, J. M., Egholm, M., Rudan, P., Brajković , D., Kućan, Z., Gušić, I., Wikström, M., Laakkonen, L., Kelso, J., Slatkin, M., and Pääbo, S. 2008. A complete Neandertal mitochondrial genome sequence determined by high-throughput sequencing. Cell, in press.

Good, J. M., Handel, M. A., and Nachman, M. W. 2008. Asymmetry and polymorphism of hybrid male sterility during the early stages of speciation in house mice. Evolution 62(1): 50-65.

Good, J. M., Hird, S., Reid, N., Demboski, J. R., Steppan, S. J., Martin-Nims, T. R., and Sullivan, J. 2008. Ancient hybridization and mitochondrial capture between two species of chipmunks. Molecular Ecology, 17:1313-1327.

Dean, M. D., Good, J. M., and Nachman, M. W. 2008. Adaptive evolution of proteins secreted during sperm maturation: an analysis of the mouse epididymal transcriptome. Molecular Biology and Evolution 25(2): 383-392.

    Saunders, M. A., Good, J. M., Lawrence, E. C., Ferrel, R. E., Li, W-H., and Nachman, M. W. 2006. Human adaptive evolution at Myostatin, a regulator of muscle growth.  American Journal of Human Genetics 79: 1089-1097.

    Good, J. M., Hayden, C. A., and Wheeler, T. J. 2006. Adaptive protein evolution and regulatory divergence in Drosophila. Molecular Biology and Evolution 23:1101-1103.

    Good, J. M., Ross, C. L., and Markow, T. A. 2006. Multiple paternity in wild-caught Drosophila mojavensis. Molecular Ecology 15:2253-2260.

    Good, J. M.
    and Nachman, M. W. 2005. Rates of protein evolution are positively correlated with timing of expression during mouse spermatogenesis. Molecular Biology and Evolution 22:1044-1052.

    Cutter, A. D., Good, J. M., Pappas, C. T., Saunders, M. A., Starrett, D. M., and Wheeler, T. 2005. Transposable element orientation bias in the Drosophila melanogater genome. Journal of Molecular Evolution 61:733-741.

    Carstens, B. C., Brunsfeld, S. J., Demboski, J. R., Good, J. M., and Sullivan, J. 2005. Investigating the evolutionary history of the Pacific Northwest mesic forest ecosystem: hypothesis testing within a comparative phylogeography framework. Evolution 59:1639-1652.

    Cutter, A. D., Payseur, B. A., Salcedo, T., Estes, A. M., Good, J. M., Wood, E., Hartl, T., Maughan, H., Strempel, J., Wang, B., Bryan, and A. C., Dellos, M. 2003. Molecular correlates of genes exhibiting RNAi phenotypes in Caenorhabditis elegans. Genome Research 13:2651-2657.

    Good, J. M., Demboski, J. R., Nagorsen, D., and Sullivan, J. 2003. Phylogeography and introgressive hybridization: chipmunks (genus Tamias) in the northern Rocky Mountains. Evolution 57:1900-1916.

    Good, J. M. and Sullivan, J. 2001. Phylogeography of the red-tailed chipmunk (Tamias ruficaudus), a northern Rocky Mountain endemic. Molecular Ecology 10:2683-2696.

PRESENTATIONS (Selected)

Good, J. M. and Nachman, M W. 2006. Asymmetry and polymorphism of hybrid male sterility during the early stages of speciation in house mice. American Society of Mammalogists, Annual Meetings, University of New Mexico, Albuquerque, NW.

    Good, J. M. 2006. Reproductive protein evolution and speciation in house mice. Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany (invited oral presentation).

    Good, J. M. and Nachman, M W. 2006. Reproductive isolation and rapid molecular evolution on the mouse X chromosome . Society of Molecular Biology and Evolution, Annual Meeting, Arizona State University, Phoenix (oral presentation).

    Good, J. M. and Nachman, M. W. 2005. Molecular population genetics of X-linked reproductive genes in Mus. SSB/SSE, Annual Meeting, University of Alaska, Fairbanks (Oral Presentation).

    Good, J. M. 2004. The evolution of male reproductive proteins in mice. NSF-IGERT Program in Genomics, Fall Symposium, University of Arizona (invited oral presentation).

    Good, J. M. and Nachman, M W. 2004. Molecular evolution and genomic location of genes expressed during spermatogenesis in the mouse. Evolutionary Genomics Meeting, University of Arizona, (poster presentation).

    Good, J. M. and Nachman, M W. 2004. Genomic distribution and molecular evolution of genes expressed only in mouse spermatogenic cells. Society of Molecular Biology and Evolution, Annual Meeting, Pennsylvania State University (poster presentation).

HONORS/AWARDS

2008 International Research Fellowship Award, National Science Foundation

2007 Postdoctoral Fellowship, Max Planck Society

2006 Robert W. Hoshaw Memorial Award, Ecology and Evolutionary Biology, University of Arizona

    2006 NSF Doctoral Dissertation Improvement Grant

    2006 Galileo Circle Scholarship, College of Science, University of Arizona

    2006 University of Arizona, EEB Departmental Small Research Grant

    2005 University of Arizona, EEB Departmental Small Research Grant

    2004 NSF Integrative Graduate Education and Research Traineeship (IGERT) in Evolutionary, Functional, and Computational Genomics, University of Arizona (1 year fellowship)

    2004 University of Arizona, EEB Departmental Small Research Grant

    2002 NSF IGERT in Evolutionary, Functional, and Computational Genomics, University of Arizona (2 year fellowship)

    2001 Award for Graduate Excellence, University of Idaho Alumni Association

    2001 University of Idaho, Graduate Student Association Travel Grant

    1998 University of Idaho, Outstanding Undergraduate Award, Biological Sciences

    1998 Phi Sigma Biological Honor Society, Beta Eta Chapter (Inductee)

    1995-1999 Dean's List, College of Letters and Sciences, University of Idaho

TEACHING EXPERIENCE

Teaching Assistant, Animal Behavior, Ecology and Evolutionary Biology, University of Arizona, 2007

Teaching Assistant, Human Genetics, University of Arizona, 2007

Teaching Assistant, Functional and Evolutionary Genomics, University of Arizona, 2006

    Teaching Assistant, Population Genetics, University of Arizona, 2006

    Teaching Assistant, Mammalogy, University of Arizona, 2004

    Teaching Assistant, Mammalogy, University of Idaho, 2000

    Teaching Assistant, Introductory Biology, University of Idaho, 1999

EDUCATION

    Ph.D., 2007, Ecology and Evolutionary Biology, University of Arizona.

    M.S., 2002, Biology, Department Biological Sciences, University of Idaho, Advisor: Dr. Jack Sullivan.

    B.S., 1999, Zoology, Magna cum Laude, University of Idaho.