Nachman Lab

Patrick Basset

CONTACT INFORMATION.

RESEARCH INTERESTS

My research activities mostly concern population genetics and evolutionary biology. My first focus has been an attempt to test different models of effective population size using genetically explicit computer simulations and analytical work. Subsequently, my work concentrated on the effect of chromosomal rearrangements on gene flow and on the speciation process. I therefore used the shrews of the Sorex araneus group as model species to test different hypotheses about chromosomal rearrangements and genetic structure.

Currently, I am interested in the characterization of genetic variation within and between closely related species of house mice. In particular, the identification of regions showing polymorphism within species but fixed differences between species may help identify genomic regions contributing to reproductive isolation. Information about the “genomic context” of the studied genes will moreover help me to address several important topics about the genomics of speciation (e.g. Is the recombination rate important?).

PUBLICATIONS

Basset P., Yannic G., Brünner H. and Hausser J., 2007. Using a Bayesian method to assign individuals to karyotypic taxa in shrew hybrid zones. Cytogenetic and Genome Research, 116: 282-288.

Basset P., Yannic G., Brünner H. and Hausser J., 2006. Restricted gene flow at specific parts of the shrew genome in chromosomal hybrid zones. Evolution, 60(8): 1718-1730.

Basset P., Yannic G. and Hausser J., 2006. Genetic and karyotypic structure in the shrews of the Sorex araneus group: Are they independent? Molecular Ecology, 15: 1577-1587.

Basset P., Yannic G., Yang F., O’Brien C.M., Graphodatsky A.S., Ferguson-Smith M.A.F., et al., 2006. Chromosome localization of microsatellite markers in the shrews of the Sorex araneus group. Chromosome Research, 14: 253-263.

Fivaz F., Basset P., Lugon-Moulin N. and Hausser J., 2003. Postglacial recolonization of the Valais ( Switzerland) by the shrew Sorex antinorii: is dispersal sex-biased? A preliminary study. Mammalia, 68(2): 253-262.

Basset P. and Hausser J., 2003. Identification of three Sorex species with microsatellite markers. Mammalia, 68(2): 245-252.

Basset P., Balloux F. and Perrin N., 2001. Testing demographic models of effective population size. Proc. R. Soc. Lond. B, 268: 311-317.

PRESENTATIONS (Selected)

Basset P., Yannic G. and Hausser J. 2005. Karyotypic versus genetic structure in the Sorex araneus group. Oral presentation at the “Seventh Meeting of the International Sorex araneus Cytogenetics Committee (ISACC)” ( St-Petersbourg, Russia).
Basset P., Yannic G., Brünner H. and Hausser J., 2005. Can chromosomal rearrangements induce barriers to gene flow at specific parts of the genome? Oral presentation at 10 th Congress of the European Society for Evolutionary Biology ( Krakow, Poland).

Basset P., Yannic G., Brünner H. and Hausser J., 2005. Restricted gene flow at specific parts of the shrew genome. Oral presentation at Biology 05 ( Basel, Switzerland).

Basset P., Yannic G., Brünner H. and Hausser J., 2004. Chromosomal rearrangements and gene flow in hybrid zones. Oral presentation at the hybridization workshop and PhD course on "Natural hybridization and introgression: from genomics to ecology" ( Denmark).

Basset P., Yannic G., Brünner H. and Hausser J., 2004. Can chromosomal rearrangements induce barriers to gene flow at specific parts of the genome? Oral presentation at Evolution 04 meeting (Fort-Collins, Co, USA).

Basset P., Yannic G., Brünner H. and Hausser J., 2004. Can Robertsonian polymorphism induce barriers to gene flow at specific parts of the genome? Poster presentation at Biology 04 meeting ( Fribourg, Switzerland).

Basset P. and Hausser J., 2002. Identification of three Sorex species with microsatellite markers. Oral presentation at the “Sixth Meeting of the International Sorex araneus Cytogenetics Committee (ISACC) and associated Symposium in Honor of Professor Karl Fredga” ( Paris, France).

Basset P., Balloux F. and Perrin N., 2001. Testing demographic models of effective population size. Oral presentation at Biology 01 (Molecular Techniques in Ecological and Evolutionary research) meeting ( Neuchâtel, Switzerland).

Basset P., Balloux F. and Perrin N., 2000. Testing demographic models of effective population size. Oral presentation at La Sage, Social systems and population genetics workshop, Lausanne University ( Switzerland).

HONORS/AWARDS

Swiss National Science Foundation young researcher grant (2006-present)

Agassiz Foundation research grant, Lausanne, Switzerland (2004)

Vaud Academic Society research grant, Lausanne, Switzerland (2004)

Swiss Zoological Society travel grant (2004)

Swiss National Science Foundation PhD grant (2000-2003)

TEACHING EXPERIENCE

Population biology, Lausanne University (DEE), 2001-2004.

Population genetics, Lausanne University (DEE), 2002-2004.

Quantitative ecology, Lausanne University (DEE), 2003-2004.

Compared zoology, Lausanne University (DEE), 2002-2003.

Animal biology, Lausanne University (DEE), 2003-2004.

Invited teacher: Insectivores in “Ecology of the small Mammals fauna in The Alps” (Nature-Museum, Chur, Switzerland), 2002.

EDUCATION

Ph.D., 2006, Lausanne University, Department of Ecology and Evolution, Laboratory of Prof. Jacques Hausser. Thesis title: Chromosomal rearrangement and genetic structure in the shrews of the Sorex araneus group.

Diploma thesis in Biology, 2000, Lausanne University, Department of Ecology and Evolution, Laboratory of Prof. Nicolas Perrin. Thesis title: Testing demographic models of effective population size.